全身状態の悪い進行性NF1変異肺腺癌患者4人のうち、3次治療トラメチニブ投与後に病状が安定したのは1人だけであり、これは対立遺伝子変異に関連している可能性がある。MAPK遺伝子のスクリーニングをさらに拡大する必要がある。- MedSci
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