Lucius Ovisibat – Compre online

Lucius Ovisibat – Compre online

EUR 329.33

1,800+ vendidos
Preco promocional

Farmacia fisica em Hong Kong, 100% de autenticidade garantida

Destaques do produto

Indicated for the treatment of cholestatic pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC), and in patients 12 months of age and older with Alagille syndrome (ALGS).

Garantias de servico

Envio direto internacionalFarmacia autorizadaRevisado por farmaceuticoGarantia de autenticidade

Especificacoes

Especificacao
400mcg*30 capsulas
Fabricante
Lucius Pharmaceuticals
Envio
Hong Kong

10000 em stock

Categorias: , Marca:

Informacoes do produto

Nome em ingles
Odevixibat
Nome generico
Odevixibat

Especificacoes

Especificacao
400mcg*30 capsulas
Fabricante
Lucius Pharmaceuticals
Envio
Hong Kong

Detalhes completos

Indicacoes

Indicated for the treatment of cholestatic pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC), and in patients 12 months of age and older with Alagille syndrome (ALGS).

Mecanismo de acao

IBAT PFIC ALGS PFIC PFIC ALGS ， IBAT ， ， [ 12.2 ]

Farmacologia

12.1 Como funciona IBAT PFIC ALGS PFIC PFIC ALGS ， IBAT ， ， [ 12.2 ]

Dosagem

2.1 3 PFIC BYLVAY 40 mcg/kg， ， 1 3 ， 40 mcg/kg ， 120 mcg/kg， 6 mg BYLVAY 19.5 kg BYLVAY 19.5 kg

Precaucoes

5.1 BYLVAY (DILI) PFIC ALGS ， 6 DILI ，2 ALGS PFIC ， 6 8 ， ， BYLVAY ，

Contraindicacoes

IBAT BYLVAY ， [ Precaucoes 5.1 ]

Interacoes medicamentosas

7.1 ， BYLVAY 4 4 [ Dosagem (2.3)] ， BYLVAY

Reacoes adversas

[ Precaucoes(5.1)] [ Precaucoes(5.2)] [ Precaucoes(5.3)] 6.1 ， ， PFIC 1 24 ， BYLVAY 40 mcg/kg 120 mcg/kg [ (14.1)]

Package Insert

Ingredients

11 BYLVAY BYLVAY IBAT ， (2S)-2-{[(2R)-2-(2-{[3,3- -7-( )-1,1- -5- -2,3,4,5- -1H-1λ 6 ,2,5- -8- ] } )-2-(4- ) ] } ， ， C 37 H 48 N 4 O 8 S 2 × 1.5 H 2 O， 768.0 g/mol 740.9 g/mol pH ， pH BYLVAY ， ， 200 600

Indications

Indicated for the treatment of cholestatic pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC), and in patients 12 months of age and older with Alagille syndrome (ALGS).

Dosagem

2.1 3 PFIC BYLVAY 40 mcg/kg， ， 1 3 ， 40 mcg/kg ， 120 mcg/kg， 6 mg BYLVAY 19.5 kg BYLVAY 19.5 kg

Reacoes adversas

[ Precaucoes(5.1)] [ Precaucoes(5.2)] [ Precaucoes(5.3)] 6.1 ， ， PFIC 1 24 ， BYLVAY 40 mcg/kg 120 mcg/kg [ (14.1)]

Contraindicacoes

IBAT BYLVAY ， [ Precaucoes 5.1 ]

Precautions

5.1 BYLVAY (DILI) PFIC ALGS ， 6 DILI ，2 ALGS PFIC ， 6 8 ， ， BYLVAY ，

Use in Pregnancy and Lactation

8.1 BYLVAY ， ，BYLVAY ， odevixibat ， 2.1

Interacoes medicamentosas

7.1 ， BYLVAY 4 4 [ Dosagem (2.3)] ， BYLVAY

Clinical Pharmacology

12 12.1 Como funciona (IBAT) (PFIC) (ALGS) PFIC PFIC ALGS ， IBAT ， ， [ (12.2)] 12.2 PFIC ALGS

Pharmacology and Toxicology

13 13.1 2 ， 100 mg/kg/ odevixibat ， AUC 231 459 Ames 1000 mg/kg/

Clinical Studies

14 14.1 PFIC BYLVAY 1 (NCT03566238) ， 24 1 62 6 17 ， PFIC 1 2 ， 1 ， ABCB11 BSEP INR 1.4 ALT ULN 10 n=20 40 mcg/kg n=23 120 mcg/kg n=19

Avaliacoes do produto (15)

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4.8★★★★★
15 avaliacoes de clientes12 compras verificadas
+o***e· 3周前
★★★★
+t***3· 1个月前
Compra verificada
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Descricao

Indicacoes

Indicated for the treatment of cholestatic pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC), and in patients 12 months of age and older with Alagille syndrome (ALGS).

Mecanismo de acao

IBAT PFIC ALGS PFIC PFIC ALGS ， IBAT ， ， [ 12.2 ]

Farmacologia

12.1 Como funciona IBAT PFIC ALGS PFIC PFIC ALGS ， IBAT ， ， [ 12.2 ]

Dosagem

2.1 3 PFIC BYLVAY 40 mcg/kg， ， 1 3 ， 40 mcg/kg ， 120 mcg/kg， 6 mg BYLVAY 19.5 kg BYLVAY 19.5 kg

Precaucoes

5.1 BYLVAY (DILI) PFIC ALGS ， 6 DILI ，2 ALGS PFIC ， 6 8 ， ， BYLVAY ，

Contraindicacoes

IBAT BYLVAY ， [ Precaucoes 5.1 ]

Interacoes medicamentosas

7.1 ， BYLVAY 4 4 [ Dosagem (2.3)] ， BYLVAY

Reacoes adversas

[ Precaucoes(5.1)] [ Precaucoes(5.2)] [ Precaucoes(5.3)] 6.1 ， ， PFIC 1 24 ， BYLVAY 40 mcg/kg 120 mcg/kg [ (14.1)]