Descricao
Indicacoes
Indicated for pulmonary arterial hypertension (PAH, WHO Group 1) in adults to reduce the risk of disease progression and hospitalization.
Mecanismo de acao
-1 (ET-1) ETA ETB , (PAH) , , , ET-1 ETA ETB ET
Farmacologia
12.1 Como funciona -1 (ET-1) ETA ETB , (PAH) , , , ET-1 ETA ETB ET
Interacoes medicamentosas
7.1 CYP3A4 CYP3A4 CYP3A4 [ (12.3)] 7.2 CYP3A4 CYP3A4 HIV CYP3A4
Reacoes adversas
• - [ Precaucoes(5.1)] • [ Precaucoes(5.2)] • [ Precaucoes(5.3)] • [ Precaucoes(5.4)] 6.1 , , 742 SERAPHIN
