L’association T-DXd et sotorasib a montré une efficacité prometteuse dans les études précliniques sur le cancer du poumon non à petites cellules porteur de la mutation KRAS G12C – Oncodaily
L’association T-DXd et sotorasib a montré une efficacité prometteuse lors d’études précliniques…
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T-DXd Plus Sotorasib in KRAS G12C-Mutant NSCLC showed durable preclinical tumor regressions and highlighted HER2 testing gaps. , ADCs, Antibody drug conjugates, HER2, HER2 expression, HER2 IHC, KRAS G12C, KRAS G12C-mutant NSCLC, KRAS inhibitor resistance, Lung cancer, NSCLC, OncoDaily Lung, Precision Oncology, preclinical oncology, Sotorasib, T-Dxd, targeted therapy, Thoracic Oncology, Trastuzumab deruxtecan, xenograft models
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索托拉西布錠 SOTOLDX Sotorasib 120mg
2021年5月29日，美國FDA宣布加速核准索拓拉西AMG510（Sotorasib）上市，用於治療腫瘤攜帶KRAS G12C突變的非小細胞肺癌（NSCLC）病患。這些患者至少接受過一種前期全身性治療。這是全球首款針對特定KRAS基因突變的抗癌療法。
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