Lucius Sotorasib – Buy online
Sotorazib is a prescription drug that targets the KRAS G12C mutant protein. It received accelerated approval from the U.S. FDA on May 28, 2021. Patients should use it only as directed by their doctor.
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索托拉西布（Sotorasib）是一种治疗KRAS突变非小细胞肺癌的靶向药。
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SOTOLDX Sotorasib 120mg
On May 29, 2021, the U.S. FDA announced accelerated approval for sotorasib (AMG510) for the treatment of patients with non-small cell lung cancer (NSCLC) harboring KRAS G12C mutations. These patients had received at least one prior systemic therapy. This is the world's first anticancer therapy targeting a specific KRAS gene mutation.
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Multiple clinical trials have demonstrated that dacomitinib has the potential to prolong progression-free survival (PFS) and overall survival (OS) compared to other EGFR-TKIs. For example, in the ARCHER-1050 clinical study, the median PFS and OS in the dacomitinib group were significantly better than those in the gefitinib group.
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Ceritinib inhibits the activity of ALK protein, thereby suppressing cells expressing ALK fusion proteins (such as EML4-ALK and NPM-ALK) to achieve a therapeutic effect in cancer treatment and, to some extent, overcomes patients' resistance to first-generation ALK inhibitors.
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Alectinib is a targeted therapy for ALK-positive non-small cell lung cancer, with clearly defined indications and dosages. During use, attention should be paid to potential side effects, and it should be used rationally under the guidance of a doctor.
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Afatinib works by irreversibly blocking ErbB family receptors (including EGFR, HER2, etc.), shutting down cancer cell signaling pathways and inhibiting tumor growth.
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