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Loratinib is a novel third-generation small molecule ALK/ROS1 dual-target inhibitor approved by the US FDA in November 2018. It is a prescription drug and should be used strictly as directed by a doctor.
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七年过去了，劳拉替尼仍在继续改写ALK阳性非小细胞肺癌的治疗规则——《药学时报》
七年过去了，仍在继续——劳拉替尼持续改写ALK阳性非小细胞肺癌的治疗规则——《药学时报》
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Lucius Dacomitinib – Buy Online
Multiple clinical trials have demonstrated that dacomitinib has the potential to prolong progression-free survival (PFS) and overall survival (OS) compared to other EGFR-TKIs. For example, in the ARCHER-1050 clinical study, the median PFS and OS in the dacomitinib group were significantly better than those in the gefitinib group.
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Ceritinib inhibits the activity of ALK protein, thereby suppressing cells expressing ALK fusion proteins (such as EML4-ALK and NPM-ALK) to achieve a therapeutic effect in cancer treatment and, to some extent, overcomes patients' resistance to first-generation ALK inhibitors.
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Alectinib is a targeted therapy for ALK-positive non-small cell lung cancer, with clearly defined indications and dosages. During use, attention should be paid to potential side effects, and it should be used rationally under the guidance of a doctor.
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Afatinib works by irreversibly blocking ErbB family receptors (including EGFR, HER2, etc.), shutting down cancer cell signaling pathways and inhibiting tumor growth.
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Regorafenib is a multi-target tyrosine kinase inhibitor primarily used to treat metastatic colorectal cancer (mCRC).
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