Lucius Mirdametinib – Buy Online
Lucius Mirdametinib – Buy Online

Lucius Mirdametinib – Buy Online

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Key Highlights

Mirdametinib is the first and only therapy approved in the European Union for adults and children 2 years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN).

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Specifications

Specification
1mg*42 capsules/box
Manufacturer
Lucius Pharmaceuticals
Shipping
Hong Kong

10000 in stock

Category: Brand:

Product Info

English Name
Mirdametinib
Generic Name
Mirdametinib

Specifications

Specification
1mg*42 capsules/box
Manufacturer
Lucius Pharmaceuticals
Shipping
Hong Kong

Full Details

Indications

Mirdametinib is the first and only therapy approved in the European Union for adults and children 2 years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN).

How It Works

Mirdametinib How It Works How It Works ，

Dosage

2 GOMEKLI 2 mg/m²， ， ， 28 21 GOMEKLI (2) 2.1 GOMEKLI GOMEKLI [ Precautions (5.1)] (EF)[ Precautions (5.2)] 2.2 GOMEKLI GOMEKLI GOMEKLI ，

Precautions

5 Precautions GOMEKLI ， ， ， ， GOMEKLI (5.1) GOMEKLI ， ， 3 ， GOMEKLI (5.2) ， ， GOMEKLI

Package Insert

Ingredients

11 GOMEKLI (R)-N-(2,3- )-3,4- -2-((2- -4- ) ) C16H14F3IN2O4， 482.20 g/mol ， 25°C 0.25 mg/mL，pH 7.2 pKa 7.96

Indications

Mirdametinib is the first and only therapy approved in the European Union for adults and children 2 years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN).

Dosage

2 GOMEKLI 2 mg/m²， ， ， 28 21 GOMEKLI (2) 2.1 GOMEKLI GOMEKLI [ Precautions (5.1)] (EF)[ Precautions (5.2)] 2.2 GOMEKLI GOMEKLI GOMEKLI ，

Precautions

5 Precautions GOMEKLI ， ， ， ， GOMEKLI (5.1) GOMEKLI ， ， 3 ， GOMEKLI (5.2) ， ， GOMEKLI

Use in Pregnancy and Lactation

8.1 How It Works[ (12.1)] ，GOMEKLI - ， mirdametinib， - ， (BSA) 2 mg/m²， ， 2% 4% 15% 20%

Clinical Pharmacology

12 12.1 How It Works 1 2 (MEK1/2) MEK1/2 (ERK) ， MEK1 MEK2 ERK NF1 ， ERK ， 12.2 -

Pharmacology and Toxicology

13 13.1 6 rasH2 ， 5 mg/kg AUC ， 2 mg/m² 15 Ames ， 1 ， 28

Clinical Studies

6.1 ， ， Precautions Description ReNeu [ (14)] n=114 NF-106 n=19 [NCT-02096471] 133 75 58 GOMEKLI 28 21 GOMEKLI 2 mg/m²， ， GOMEKLI 133 ，62% ，38% ，12%

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Description

Indications

Mirdametinib is the first and only therapy approved in the European Union for adults and children 2 years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN).

How It Works

Mirdametinib How It Works How It Works ，

Dosage

2 GOMEKLI 2 mg/m²， ， ， 28 21 GOMEKLI (2) 2.1 GOMEKLI GOMEKLI [ Precautions (5.1)] (EF)[ Precautions (5.2)] 2.2 GOMEKLI GOMEKLI GOMEKLI ，

Precautions

5 Precautions GOMEKLI ， ， ， ， GOMEKLI (5.1) GOMEKLI ， ， 3 ， GOMEKLI (5.2) ， ， GOMEKLI