Buy Lucius Nintedanib online

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Key Highlights

Used to treat idiopathic pulmonary fibrosis (IPF) in adults, chronic fibrosing interstitial lung disease (ILD) with a progressive phenotype in adults, and to slow the decline of lung function in adults with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Service Promise

Direct from JapanLicensed PharmacyPharmacist CheckedEditable in Admin

Specifications

Specification
100mg*60 150mg*60
Manufacturer
Lucius Pharmaceuticals
Shipping
Hong Kong
SKU: N/A Categories: , Tag: Brand:

Product Info

English Name
Nintedanib
Generic Name
Nintedanib

Specifications

Specification
100mg*60 150mg*60
Manufacturer
Lucius Pharmaceuticals
Shipping
Hong Kong

Full Details

Indications

Used to treat idiopathic pulmonary fibrosis (IPF) in adults, chronic fibrosing interstitial lung disease (ILD) with a progressive phenotype in adults, and to slow the decline of lung function in adults with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

How It Works

, RTK nRTK RTK PDGFR α β FGFR 1 3 VEGFR 1 3 1 CSF1R Fms -3 FLT-3 FLT-3 , ILD ATP , , ILD

Pharmacology

12.1 How It Works , (RTK) (nRTK) RTK (PDGFR) α β (FGFR) 1 3 (VEGFR) 1 3 1 (CSF1R) Fms -3 (FLT-3) FLT-3 , (ILD) (ATP) ,

Precautions

5.1 Child-Pugh B Child-Pugh C [ (8.6) (12.3)] Child-Pugh A [ Dosage (2.3)] 5.2 DILI , DILI

Drug Interactions

7.1 P- (P-gp) CYP3A4 P-gp , CYP3A4 [ (12.3)] P-gp CYP3A4 , 60% P-gp CYP3A4 [ (12.3)] ,

Adverse Reactions

[ Precautions(5.2)] [ Precautions(5.3)] - [ Precautions(5.4)] [ Precautions(5.5)] [ Precautions(5.6)] [ Precautions(5.7)] [ Precautions(5.8)] 6.1 ,

Package Insert

Ingredients

11 , [ How It Works(12.1)] , 1H- -6- ,2,3- -3-[[[4-[ [(4- -1- ) ] ] ] ] ]-2- -, ,(3Z)-, (1:1) , C31H33N5O4ꞏC2H6O3S, 649.76 g/mol , 100 150 120.40 180.60 Medi

Indications

Used to treat idiopathic pulmonary fibrosis (IPF) in adults, chronic fibrosing interstitial lung disease (ILD) with a progressive phenotype in adults, and to slow the decline of lung function in adults with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Adverse Reactions

[ Precautions(5.2)] [ Precautions(5.3)] - [ Precautions(5.4)] [ Precautions(5.5)] [ Precautions(5.6)] [ Precautions(5.7)] [ Precautions(5.8)] 6.1 ,

Precautions

5.1 Child-Pugh B Child-Pugh C [ (8.6) (12.3)] Child-Pugh A [ Dosage (2.3)] 5.2 DILI , DILI

Drug Interactions

7.1 P- (P-gp) CYP3A4 P-gp , CYP3A4 [ (12.3)] P-gp CYP3A4 , 60% P-gp CYP3A4 [ (12.3)] ,

Clinical Pharmacology

12 12.1 How It Works , (RTK) (nRTK) RTK (PDGFR) α β (FGFR) 1-3 (VEGFR) 1-3 1 (CSF1R) Fms -3 (FLT-3) FLT-3 , (ILD) ATP , , ILD nRTK Lck Lyn

Pharmacology and Toxicology

13 13.1 10 30 mg/kg/ MRHD AUC 4 , MRHD AUC, 100 mg/kg/ 3 ,

Clinical Studies

14 14.1 II 1 [NCT00514683] III 2 [NCT01335464] 3 [NCT01335477] 1231 (IPF) , , 150 mg 52 2 3 1 3:2 1 1:1 150 mg , 52

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Description

Indications

Used to treat idiopathic pulmonary fibrosis (IPF) in adults, chronic fibrosing interstitial lung disease (ILD) with a progressive phenotype in adults, and to slow the decline of lung function in adults with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

How It Works

, RTK nRTK RTK PDGFR α β FGFR 1 3 VEGFR 1 3 1 CSF1R Fms -3 FLT-3 FLT-3 , ILD ATP , , ILD

Pharmacology

12.1 How It Works , (RTK) (nRTK) RTK (PDGFR) α β (FGFR) 1 3 (VEGFR) 1 3 1 (CSF1R) Fms -3 (FLT-3) FLT-3 , (ILD) (ATP) ,

Precautions

5.1 Child-Pugh B Child-Pugh C [ (8.6) (12.3)] Child-Pugh A [ Dosage (2.3)] 5.2 DILI , DILI

Drug Interactions

7.1 P- (P-gp) CYP3A4 P-gp , CYP3A4 [ (12.3)] P-gp CYP3A4 , 60% P-gp CYP3A4 [ (12.3)] ,

Adverse Reactions

[ Precautions(5.2)] [ Precautions(5.3)] - [ Precautions(5.4)] [ Precautions(5.5)] [ Precautions(5.6)] [ Precautions(5.7)] [ Precautions(5.8)] 6.1 ,

Additional information

Specification

100mg*60粒, 150mg*60粒